On November 6, 2012, two states' voters — Colorado's and Washington's — approved history-making measures to end their states' prohibition on marijuana, and Massachusetts voters approved a medical marijuana initiative. In Oregon and Arkansas, voters narrowly defeated reform measures, and in Montana, voters approved the legislature's decision to restrict the state's medical marijuana law.
| State | Initiative | Sponsored by | MPP supports? | Results |
| Arkansas |
Issue 5: Authorize the use of marijuana for medical purposes. |
Arkansans for Compassionate Care (funded primarily by MPP)
|
Yes |
LOSS 48.56%-51.44% |
| Colorado |
Amendment 64: Allow the personal possession and cultivation of marijuana by adults who are 21 and older and allow regulated sales. |
Campaign to Regulate Marijuana Like Alcohol (funded and staffed primarily by MPP) |
Yes |
WIN 55.33%-44.67% |
| Massachusetts |
Question 3: Authorize the use of marijuana for medical purposes. |
Committee for Compassionate Medicine |
Yes |
WIN 63.33%-36.67%
|
| Montana |
IR-124: Uphold the legislature’s gutting of the state’s medical marijuana law, including by banning providers from receiving compensation. |
Patients for Reform, not Repeal (group that worked against the legislature’s restrictive law) |
No |
WIN (A DEFEAT FOR PATIENTS) 57.25%-42.75% |
| Oregon |
Measure 80: Repeal Oregon's marijuana prohibition and replace it with a system of taxation and regulation.
|
Yes on Measure 80 Campaign
|
Yes |
LOSS 46.58%-53.42%
|
Washington
|
Initiative 502: Allow the possession of an ounce of marijuana by adults who are 21 and older and allow regulated sales. |
New Approach Washington
|
Yes |
WIN 55.70%-44.30%
|